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Carrier cell-based delivery of replication-competent HSV-1 mutants enhances antitumor effect for ovarian cancer
Oncolytic viruses capable of tumor-selective replication and cytolysis have shown early promise as cancer therapeutics. We have developed replication-competent attenuated herpes simplex virus type 1 (HSV-1) mutants, named HF10 and Hh101, which have been evaluated for their oncolytic activities. Howe...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025316/ https://ncbi.nlm.nih.gov/pubmed/20885447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.53 |
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