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Elevated 4-hydroxyhexenal in Alzheimer’s disease (AD) progression

Multiple studies have demonstrated elevations of α, β-unsaturated aldehydes including, 4-hydroxynonenal (HNE) and acrolein, in vulnerable regions of mild cognitive impairment (MCI), preclinical Alzheimer’s disease (PCAD), and late-stage Alzheimer’s disease (LAD) brain. However, there has been limite...

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Autori principali: Bradley, M. A., Xiong-Fister, S., Markesbery, W. R., Lovell, M. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025307/
https://ncbi.nlm.nih.gov/pubmed/20965613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2010.08.016
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