Enhanced diagnosis of HIV-1 associated tuberculosis by relating T-SPOT.TB and CD4 counts

BACKGROUND: The sensitivity of the tuberculin skin test is impaired in HIV-1 infected persons. ELISpot-based detection of immune sensitisation may be less affected. Furthermore, the quantitative response can be related to the CD4 count, potentially improving specificity for active disease. METHODS:...

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Hlavní autoři: ONI, Tolu, PATEL, Janisha, GIDEON, Hannah P, SELDON, Ronnett, WOOD, Kathryn, HLOMBE, Yekiwe, WILKINSON, Katalin A, RANGAKA, Molebogeng X, MENDELSON, Marc, WILKINSON, Robert J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025278/
https://ncbi.nlm.nih.gov/pubmed/20075047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00171509
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