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Recombinant E.coli prototype strains for in vivo glycorandomization

Glycoconjugation is a powerful tool to enhance the pharmacodymanics and/or pharmacokinetics of small molecule-based therapeutics, including natural products1. Yet, studies designed to systematically understand or exploit the attachment of carbohydrates in drug discovery remain limited by the availab...

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Hlavní autoři: Williams, Gavin J, Yang, Jie, Zhang, Changsheng, Thorson, Jon S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025069/
https://ncbi.nlm.nih.gov/pubmed/20886903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100267k
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