The Kinetics of Intramolecular Distribution of (15)N in Uric Acid after Administration of [(15)N]Glycine A REAPPRAISAL OF THE SIGNIFICANCE OF PREFERENTIAL LABELING OF N-(3 + 9) OF URIC ACID IN PRIMARY GOUT
The concept of an abnormality of glutamine metabolism in primary gout was first proposed on the basis of isotope data: when [(15)N]glycine was administered to gouty subjects, there was disproportionately great enrichment of N-(3 + 9) of uric acid, which derive from the amide-N of glutamine. An undul...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1973
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302506/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4353999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107438 |
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