Apoptosis-related deregulation of proteolytic activities and high serum levels of circulating nucleosomes and DNA in blood correlate with breast cancer progression

BACKGROUND: As cell-free circulating DNA exists predominantly as mono- and oligonucleosomes, the focus of the current study was to examine the interplay of circulating nucleosomes, DNA, proteases and caspases in blood of patients with benign and malignant breast diseases. METHODS: The concentrations...

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Bibliografiska uppgifter
Huvudupphovsmän: Roth, Carina, Pantel, Klaus, Müller, Volkmar, Rack, Brigitte, Kasimir-Bauer, Sabine, Janni, Wolfgang, Schwarzenbach, Heidi
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024991/
https://ncbi.nlm.nih.gov/pubmed/21211028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-4
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