Llwytho...
Ricin Inhibits Activation of the Unfolded Protein Response by Preventing Splicing of the HAC1 mRNA
Ricin A chain (RTA) inhibits protein synthesis by removing a specific adenine from the highly conserved α-sarcin/ricin loop in the large rRNA. Expression of RTA with its own signal sequence in yeast resulted in its translocation into the endoplasmic reticulum (ER) and subsequent glycosylation. Becau...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2008
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024914/ https://ncbi.nlm.nih.gov/pubmed/18180297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707981200 |
| Tagiau: |
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