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A caveat for T cell transfer studies: generation of cytotoxic anti-Thy1.2 antibodies in Thy1.1 congenic mice given Thy1.2+ tumors or T cells

Thy1.1 congenic B6.PL mice were used to simultaneously monitor Thy1.2+ E.G7-OVA tumors transplanted in the a.c. of the eye and i.v.-transferred tumor-specific Thy1.2+ CTLs to determine mechanisms that inhibit the tumoricidal activity of CTL responses in mice with established ocular tumors. Transferr...

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Autors principals: McKenna, Kyle C., Miguel, Rodolfo D. Vicetti, Beatty, Kelly M., Bilonick, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024899/
https://ncbi.nlm.nih.gov/pubmed/20959413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0610333
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