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The utility of mass spectrometry-based proteomic data for validation of novel alternative splice forms reconstructed from RNA-Seq data: a preliminary assessment

BACKGROUND: Most mass spectrometry (MS) based proteomic studies depend on searching acquired tandem mass (MS/MS) spectra against databases of known protein sequences. In these experiments, however, a large number of high quality spectra remain unassigned. These spectra may correspond to novel peptid...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ning, Kang, Nesvizhskii, Alexey I
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024872/
https://ncbi.nlm.nih.gov/pubmed/21172049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S11-S14
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