Binding of Cyclic Diguanylate in the Non-catalytic EAL Domain of FimX Induces a Long-range Conformational Change

FimX is a multidomain signaling protein required for type IV pilus biogenesis and twitching motility in the opportunistic pathogen Pseudomonas aeruginosa. FimX is localized to the single pole of the bacterial cell, and the unipolar localization is crucial for the correct assembly of type IV pili. Fi...

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Bibliographic Details
Main Authors: Qi, Yaning, Chuah, Mary Lay Cheng, Dong, Xueming, Xie, Kailing, Luo, Zhen, Tang, Kai, Liang, Zhao-Xun
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024786/
https://ncbi.nlm.nih.gov/pubmed/21098028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.196220
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