A Dbf4 Mutant Contributes to Bypassing the Rad53-mediated Block of Origins of Replication in Response to Genotoxic Stress

An intra-S phase checkpoint slows the rate of DNA replication in response to DNA damage and replication fork blocks in eukaryotic cells. In the budding yeast Saccharomyces cerevisiae, such down-regulation is achieved through the Rad53 kinase-dependent block of origins of replication. We have identif...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Duch, Alba, Palou, Gloria, Jonsson, Zophonias O., Palou, Roger, Calvo, Enrique, Wohlschlegel, James, Quintana, David G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
DNA and Chromosomes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024743/
https://ncbi.nlm.nih.gov/pubmed/21098477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190843
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