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Alcohol Induces RNA Polymerase III-dependent Transcription through c-Jun by Co-regulating TATA-binding Protein (TBP) and Brf1 Expression

Chronic alcohol consumption is associated with steatohepatitis and cirrhosis, enhancing the risk for hepatocellular carcinoma. RNA polymerase (pol) III transcribes a variety of small, untranslated RNAs, including tRNAs and 5S rRNAs, which determine the biosynthetic capacity of cells. Increased RNA p...

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Detalhes bibliográficos
Main Authors: Zhong, Shuping, Machida, Keigo, Tsukamoto, Hide, Johnson, Deborah L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024733/
https://ncbi.nlm.nih.gov/pubmed/21106530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192955
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