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Immature T-cell clustering and efficient differentiation require the polarity protein Scribble

T-cell polarization is required for cell migration and cell–cell interactions, cellular behaviors crucial for lymphocyte differentiation. Despite expression of the epithelial polarity network in T cells, neither its contribution to thymocyte polarity nor its requirement during development is known....

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Detalhes bibliográficos
Main Authors: Pike, Kelly A., Kulkarni, Sarang, Pawson, Tony
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024664/
https://ncbi.nlm.nih.gov/pubmed/21189299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018224108
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