Fibulin-4 regulates expression of the tropoelastin gene and consequent elastic-fibre formation by human fibroblasts

Elastic fibres are essential for normal physiology in numerous tissues, including arteries, lungs and skin. Fibulin-4 is an elastic-fibre-associated glycoprotein that is indispensable for elastic-fibre formation in mice. However, the mechanism by which fibulin-4 executes this function remains to be...

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Main Authors: CHEN, Qiuyun, ZHANG, Teng, ROSHETSKY, Joseph F., OUYANG, Zhufeng, ESSERS, Jeroen, FAN, Chun, WANG, Qing, HINEK, Aleksander, PLOW, Edward F., DiCORLETO, Paul E.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024593/
https://ncbi.nlm.nih.gov/pubmed/19627254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20090993
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