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Biologic and Immunologic Characterization and Physical Separation of ACTH and ACTH Fragments in the Ectopic ACTH Syndrome

Extracts of tumors from 32 patients with the ectopic ACTH syndrome were subjected to simultaneous bioassay and radioimmunoassays for ACTH. Radioimmunoassays were performed using three antisera, one of which reacts with the extreme N-terminal 1-13 amino acid sequence of ACTH, the second with the N-te...

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Publicado en:J Clin Invest
Principais autores: Orth, David N., Nicholson, Wendell E., Mitchell, William M., Island, Donald P., Liddle, Grant W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1973
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4352463/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107357
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