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Hemoglobin Messenger RNA from Human Bone Marrow ISOLATION AND TRANSLATION IN HOMOZYGOUS AND HETEROZYGOUS β-THALASSEMIA

A method for isolating human hemoglobin messenger RNA (mRNA) from bone marrow cells was developed to investigate the molecular basis for the defect in globin synthesis in beta thalassemia. Active mRNA was isolated from the bone marrow cells and peripheral reticulocytes of patients with homozygous be...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Nienhuis, A. W., Canfield, P. H., Anderson, W. F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1973
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302449/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4718962/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107355
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