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The Microbe-Derived Short Chain Fatty Acid Butyrate Targets miRNA-Dependent p21 Gene Expression in Human Colon Cancer

Colonic microbiota ferment non-absorbed dietary fiber to produce prodigious amounts of short chain fatty acids (SCFAs) that benefit the host through a myriad of metabolic, trophic, and chemopreventative effects. The chemopreventative effects of the SCFA butyrate are, in part, mediated through induct...

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Detalhes bibliográficos
Main Authors: Hu, Shien, Dong, Tien Sy, Dalal, Sushila R., Wu, Feng, Bissonnette, Marc, Kwon, John H., Chang, Eugene B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024403/
https://ncbi.nlm.nih.gov/pubmed/21283757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016221
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