An open randomized clinical trial in comparing two artesunate-based combination treatments on Plasmodium falciparum malaria in Nigerian children: artesunate/sulphamethoxypyrazine/pyrimethamine (fixed dose over 24 hours) versus artesunate/amodiaquine (fixed dose over 48 hours)

BACKGROUND: Several studies have demonstrated the efficacy of artemisinin-combination therapy (ACT) across malaria zones of the world. Fixed dose ACT with shorter courses and fewer tablets may be key determinants to ease of administration and compliance. METHODS: Children aged one year to 13 years p...

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Autori principali: Ayede, Idowu Adejumoke, Falade, Adegoke Gbadegesin, Sowunmi, Akintunde, Jansen, Frans Herwig
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024282/
https://ncbi.nlm.nih.gov/pubmed/21194422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-378
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