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High relaxivity MRI contrast agents part 2: Optimization of inner- and second-sphere relaxivity

RATIONALE AND OBJECTIVES: The observed relaxivity of gadolinium based contrast agents has contributions from the water molecule(s) that bind directly to the gadolinium ion (inner-sphere water), long lived water molecules and exchangeable protons that make up the second-sphere of coordination, and wa...

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Main Authors: Jacques, Vincent, Dumas, Stephane, Sun, Wei-Chuan, Troughton, Jeffrey S., Greenfield, Matthew T., Caravan, Peter
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024144/
https://ncbi.nlm.nih.gov/pubmed/20808234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/RLI.0b013e3181ee6a49
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