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Evolutionary origins of oxygen sensing in animals

Oxygen is required for aerobic energy production but its levels have to be tightly regulated to avoid deleterious effects. Thus, animals have evolved mechanisms to monitor and respond to fluctuations in oxygen availability. Here, the evolution of the HIF system is discussed in light of a report that...

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Main Authors: Rytkönen, Kalle T, Storz, Jay F
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024129/
https://ncbi.nlm.nih.gov/pubmed/21109778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.192
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