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miR-146a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation
MicroRNAs are phenotypic regulators of vascular smooth muscle cells (VSMCs). In this paper, we demonstrate that miR-146a targets the Krüppel-like factor 4 (KLF4) 3′-untranslated region and has an important role in promoting VSMC proliferation in vitro and vascular neointimal hyperplasia in vivo. Sil...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3024123/ https://ncbi.nlm.nih.gov/pubmed/21109779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.172 |
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