miR-146a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation

MicroRNAs are phenotypic regulators of vascular smooth muscle cells (VSMCs). In this paper, we demonstrate that miR-146a targets the Krüppel-like factor 4 (KLF4) 3′-untranslated region and has an important role in promoting VSMC proliferation in vitro and vascular neointimal hyperplasia in vivo. Sil...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sun, Shao-guang, Zheng, Bin, Han, Mei, Fang, Xin-mei, Li, Hui-xuan, Miao, Sui-bing, Su, Ming, Han, Yi, Shi, Hui-jing, Wen, Jin-kun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Scientific Reports
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024123/
https://ncbi.nlm.nih.gov/pubmed/21109779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.172
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