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The Nrf2–Keap1 cellular defense pathway and heat shock protein 70 (Hsp70) response. Role in protection against oxidative stress in early neonatal unilateral ureteral obstruction (UUO)

Perturbation of renal tubular antioxidants and overproduction of reactive oxygen species may amplify the proinflammatory state of renal obstruction, culminating in oxidative stress and tubular loss. Here, we analyzed the heat shock protein 70 (Hsp70) response and the function and signal transduction...

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Main Authors: Rinaldi Tosi, Martin E., Bocanegra, Victoria, Manucha, Walter, Gil Lorenzo, Andrea, Vallés, Patricia G.
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024087/
https://ncbi.nlm.nih.gov/pubmed/20734248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-010-0221-y
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