Electroconvulsive shock ameliorates disease processes and extends survival in huntingtin mutant mice

Huntington's disease (HD) is an inherited neurodegenerative disorder caused by expanded polyglutamine repeats in the huntingtin (Htt) protein. Mutant Htt may damage and kill striatal neurons by a mechanism involving reduced production of brain-derived neurotrophic factor (BDNF) and increased ox...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mughal, Mohamed R., Baharani, Akanksha, Chigurupati, Srinivasulu, Son, Tae Gen, Chen, Edmund, Yang, Peter, Okun, Eitan, Arumugam, Thiruma, Chan, Sic L., Mattson, Mark P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024043/
https://ncbi.nlm.nih.gov/pubmed/21106706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq512
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