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Detailed Analysis of Function Divergence in a Large and Diverse Domain Superfamily: Towards a Refined Protocol of Function Classification

Some superfamilies contain large numbers of protein domains with very different functions. The ability to refine the functional classification of domains within these superfamilies is necessary for better understanding the evolution of functions and to guide function prediction of new relatives. To...

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Bibliographic Details
Main Authors: Dessailly, Benoit H., Redfern, Oliver C., Cuff, Alison L., Orengo, Christine A.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023962/
https://ncbi.nlm.nih.gov/pubmed/21070951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.08.017
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