Methylation of the Candidate Biomarker TCF21 Is Very Frequent Across A Spectrum of Early Stage Non-Small Cell Lung Cancers

BACKGROUND: The transcription factor TCF21 is involved in mesenchymal-to-epithelial differentiation and was shown to be aberrantly hypermethylated in lung and head and neck cancers. Because of its reported high frequency of hypermethylation in lung cancer, we sought to characterize the stages and ty...

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Detalhes bibliográficos
Main Authors: Richards, Kristy L., Zhang, Baili, Sun, Menghong, Dong, Wenli, Churchill, Jennifer, Bachinski, Linda L., Wilson, Charmaine D., Baggerly, Keith A., Yin, Guosheng, Neil Hayes, D., Wistuba, Ignacio I., Krahe, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023841/
https://ncbi.nlm.nih.gov/pubmed/20945327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25472
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