Transcription factor c-Myb promotes the invasion of hepatocellular carcinoma cells via increasing osteopontin expression

BACKGROUND: Specific gene expression is tightly regulated by various transcription factors. Osteopontin (OPN) is a phosphoprotein that mediates hepatocellular carcinoma (HCC) progression and metastasis. However, the mechanism of OPN up-regulation in HCC metastasis remains to be clarified. METHODS: O...

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Bibliographic Details
Main Authors: Chen, Rong-Xin, Xia, Yun-Hong, Xue, Tong-Chun, Ye, Sheng-Long
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023683/
https://ncbi.nlm.nih.gov/pubmed/21190594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-172
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