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The bacterial virulence factor NleA's involvement in intestinal tight junction disruption during enteropathogenic E. coli infection is independent of its putative PDZ binding domain

Enteropathogenic Escherichia coli (EPEC) is an enteric pathogen able to cause severe diarrhea. Once adhered to the small intestine, EPEC disrupts tight junctions that are important for intestinal barrier function. This disruption is dependent on the bacterial type III secretion system, as well as th...

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Main Authors: Thanabalasuriar, Ajitha, Koutsouris, Athanasia, Hecht, Gail, Gruenheid, Samantha
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023590/
https://ncbi.nlm.nih.gov/pubmed/21326920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.1.2.11685
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