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Monolysocardiolipin: improved preparation with high yield

A simple, high-yielding preparation of monolysocardiolipin (MLCL) by phospholipase A2 hydrolysis of cardiolipin (CL) in methanol on a semi-preparative scale is described. In methanol, phospholipase A2 preferentially hydrolyzes CL to MLCL. This selectivity results in ∼80% yield of MLCL. The synthesiz...

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Bibliografske podrobnosti
Main Authors: Kim, Junhwan, Hoppel, Charles L.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023560/
https://ncbi.nlm.nih.gov/pubmed/20959418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D010587
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