Tamm-Horsfall Glycoprotein Interacts with Renal Outer Medullary Potassium Channel ROMK2 and Regulates Its Function

Tamm-Horsfall glycoprotein (THGP) or Uromodulin is a membrane protein exclusively expressed along the thick ascending limb (TAL) and early distal convoluted tubule (DCT) of the nephron. Mutations in the THGP encoding gene result in Familial Juvenile Hyperuricemic Nephropathy (FJHN), Medullary Cystic...

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Bibliografiske detaljer
Main Authors: Renigunta, Aparna, Renigunta, Vijay, Saritas, Turgay, Decher, Niels, Mutig, Kerim, Waldegger, Siegfried
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023518/
https://ncbi.nlm.nih.gov/pubmed/21081491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.149880
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