NF-κB Down-regulates Expression of the B-lymphoma Marker CD10 through a miR-155/PU.1 Pathway

Cell-surface protein CD10 is a prognostic marker for diffuse large B-cell lymphoma (DLBCL), where high expression of CD10 is found in the germinal center B-cell (GCB) subtype and CD10 expression is low or absent in the activated B-cell (ABC) subtype. As compared with the GCB subtype, patients with A...

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Bibliographische Detailangaben
Hauptverfasser: Thompson, Ryan C., Herscovitch, Melanie, Zhao, Ian, Ford, Tyler J., Gilmore, Thomas D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023462/
https://ncbi.nlm.nih.gov/pubmed/20947507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.177063
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