SA 4503 attenuates cocaine-induced hyperactivity and enhances methamphetamine substitution for a cocaine discriminative stimulus

Cocaine exhibits preferential (∼15-fold) affinity for σ(1) over σ(2) sigma receptors, and previous research has shown an interaction of σ(1) receptor-selective ligands and cocaine's behavioral effects. The present study investigated the effect of the putative sigma receptor agonist SA 4503 (1-(...

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Main Authors: Rodvelt, Kelli R., Lever, Susan Z., Lever, John R., Blount, Lucas R., Fan, Kuo-Hsien, Miller, Dennis K.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023454/
https://ncbi.nlm.nih.gov/pubmed/21115033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.11.016
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