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SA 4503 attenuates cocaine-induced hyperactivity and enhances methamphetamine substitution for a cocaine discriminative stimulus
Cocaine exhibits preferential (∼15-fold) affinity for σ(1) over σ(2) sigma receptors, and previous research has shown an interaction of σ(1) receptor-selective ligands and cocaine's behavioral effects. The present study investigated the effect of the putative sigma receptor agonist SA 4503 (1-(...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3023454/ https://ncbi.nlm.nih.gov/pubmed/21115033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbb.2010.11.016 |
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