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Adenosine can mediate its actions through generation of reactive oxygen species

Adenosine is an important cerebral vasodilator, but mediating mechanisms are not understood. We investigated the expression of adenosine receptor subtypes in isolated cerebral arterial muscle cells (CAMCs), and their role in adenosine-induced superoxide (O(2)(−)) generation and reduction in cerebral...

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Detalhes bibliográficos
Main Authors: Gebremedhin, Debebe, Weinberger, Brian, Lourim, David, Harder, David R
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023402/
https://ncbi.nlm.nih.gov/pubmed/20531463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.70
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