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Acute Reversal of Experimental Diabetic Ketoacidosis in the Rat with (+)-Decanoylcarnitine

The effect of (+)-decanoylcarnitine, a potent inhibitor of long-chain acylcarnitine transferase, was tested for its ability to inhibit hepatic ketogenesis both in the isolated perfused liver and in vivo in severely ketotic alloxan diabetic rats. In vitro the inhibitor caused an almost complete block...

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Pubblicato in:J Clin Invest
Autori principali: McGarry, J. Denis, Foster, Daniel W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1973
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302335/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4632691/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107252
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