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The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia

Organotypic cultures of primary human airway epithelial cells have been used to investigate the morphology, ion and fluid transport, innate immunity, transcytosis, infection, inflammation, signaling, cilia, and repair functions of this complex tissue. However, we do not know how closely these cultur...

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Detalhes bibliográficos
Main Authors: Pezzulo, Alejandro A., Starner, Timothy D., Scheetz, Todd E., Traver, Geri L., Tilley, Ann E., Harvey, Ben-Gary, Crystal, Ronald G., McCray, Paul B., Zabner, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023285/
https://ncbi.nlm.nih.gov/pubmed/20971803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00256.2010
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