INSULIN RESISTANCE IS ASSOCIATED WITH ALZHEIMER-LIKE REDUCTIONS IN REGIONAL CEREBRAL GLUCOSE METABOLISM FOR COGNITIVELY NORMAL ADULTS WITH PRE-DIABETES OR EARLY TYPE 2 DIABETES

BACKGROUND: Insulin resistance is a causal factor in pre-diabetes and type 2 diabetes (T2D), and also increases the risk of developing Alzheimer’s disease (AD). Reductions in cerebral glucose metabolic rate (CMRglu) as measured by fluorodeoxyglucose positron emission tomography (FDG PET) in parietot...

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Hauptverfasser: Baker, Laura D., Cross, Donna, Minoshima, Satoshi, Belongia, Dana, Watson, G. Stennis, Craft, Suzanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023149/
https://ncbi.nlm.nih.gov/pubmed/20837822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2010.225
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