Thymus-specific serine protease contributes to the diversification of the functional endogenous CD4 T cell receptor repertoire

Thymus-specific serine protease (TSSP) is a novel protease that may contribute to the generation of the peptide repertoire presented by MHC class II molecules in the thymus. Although TSSP deficiency has no quantitative impact on the development of CD4 T cells expressing a polyclonal T cell receptor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Viret, Christophe, Lamare, Camille, Guiraud, Martine, Fazilleau, Nicolas, Bour, Agathe, Malissen, Bernard, Carrier, Alice, Guerder, Sylvie
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2011
Schlagworte:
Brief Definitive Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3023141/
https://ncbi.nlm.nih.gov/pubmed/21173102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100027
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