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Twelve Months of Nightly Zolpidem Does Not Lead to Dose Escalation: A Prospective Placebo-Controlled Study

STUDY OBJECTIVES: To assess hypnotic self-administration and likelihood of dose escalation over 12 months of nightly use of zolpidem versus placebo in primary insomniacs. DESIGN: Randomized, double-blind, placebo-controlled, clinical trial. SETTING: Outpatient with tri-monthly one-week, sleep labora...

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Detalhes bibliográficos
Main Authors: Roehrs, Timothy A., Randall, Surilla, Harris, Erica, Maan, Renee, Roth, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022941/
https://ncbi.nlm.nih.gov/pubmed/21286241
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