A molecular inversion probe assay for detecting alternative splicing

ABSRACT: BACKGROUND: A sensitive, high-throughput method for monitoring pre-mRNA splicing on a genomic scale is needed to understand the spectrum of alternatively spliced mRNA in human cells. RESULTS: We adapted Molecular Inversion Probes (MIPs), a padlock-probe based technology, for the multiplexed...

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Bibliographic Details
Main Authors: Lin, Shengrong, Wang, Wenyi, Palm, Curtis, Davis, Ronald W, Juneau, Kara
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022918/
https://ncbi.nlm.nih.gov/pubmed/21167051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-712
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