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Erythrocyte Hb-S Concentration AN IMPORTANT FACTOR IN THE LOW OXYGEN AFFINITY OF BLOOD IN SICKLE CELL ANEMIA

The blood in sickle cell anemia has a very low oxygen affinity and, although 2,3-diphosphoglycerate (2,3-DPG) is increased, there is doubt as to whether this is the only factor responsible. In this study of 15 patients with sickle cell anemia (Hb SS) no correlation was found between oxygen affinity...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Seakins, M., Gibbs, W. N., Milner, P. F., Bertles, J. F.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1973
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302272/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4683881/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107199
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