Molecular cloning, characterization, genomic organization and promoter analysis of the α1,6-fucosyltransferase gene (fut8) expressed in the rat hybridoma cell line YB2/0

BACKGROUND: The rat hybridoma cell line YB2/0 appears a good candidate for the large-scale production of low fucose recombinant mAbs due to its lower expression of fut8 gene than other commonly used rodent cell lines. However, important variations of the fucose content of recombinant mAbs are observ...

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Detalhes bibliográficos
Main Authors: Teylaert, Béatrice, Meurice, Edwige, Bobowski, Marie, Harduin-Lepers, Anne, Gaucher, Christine, Fontayne, Alexandre, Jorieux, Sylvie, Delannoy, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022693/
https://ncbi.nlm.nih.gov/pubmed/21208406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-11-1
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