Hemoglobin Olympia (β20 Valine → Methionine): An Electrophoretically Silent Variant Associated with High Oxygen Affinity and Erythrocytosis

In a family with erythrocytosis, electrophoretic and chromatographic studies failed to demonstrate a hemoglobin variant. However, the oxygen dissociation curves of affected individuals were shifted to the left of normal and this shift persisted when oxygen equilibria were studied in 2.3-diphosphogly...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Stamatoyannopoulos, George, Nute, Peter E., Adamson, John W., Bellingham, A. J., Funk, Donald
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1973
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4683875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107190
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