Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection

BACKGROUND: Mannose-binding lectin (MBL), a pattern recognition innate immune molecule, inhibits influenza A virus infection in vitro. MBL deficiency due to gene polymorphism in humans has been associated with infection susceptibility. These clinical observations were confirmed by animal model studi...

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Detalhes bibliográficos
Main Authors: Chang, Wei-Chuan, White, Mitchell R, Moyo, Patience, McClear, Sheree, Thiel, Steffen, Hartshorn, Kevan L, Takahashi, Kazue
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022599/
https://ncbi.nlm.nih.gov/pubmed/21182784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-11-64
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