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Another Tier for Caspase Regulation: IAPs as NEDD8 E3 ligases
Many Inhibitor of Apoptosis Proteins (IAPs) function as E3 ligases to ubiquitinate important cell death proteins, including caspases. Broemer et al. (2010) report recently in Molecular Cell that IAPs can also inhibit caspases by promoting conjugation of the UBL NEDD8.
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022555/ https://ncbi.nlm.nih.gov/pubmed/21145494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.11.014 |
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