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Alcohol-Induced Interactive Phosphorylation of Src and Toll-like Receptor Regulates the Secretion of Inflammatory Mediators by Human Astrocytes

Secretion of pro-inflammatory molecules by astrocytes after alcohol treatment was shown to be associated with neuroinflammation. We hypothesized that activation of cytosolic phospholipase A2 (cPLA2) and cyclooxygenase (COX-2) by ethanol in astrocytes enhanced the secretion of inflammatory agents via...

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Bibliografiska uppgifter
Huvudupphovsmän: Floreani, Nicholas A., Rump, Travis J., Abdul Muneer, P. M., Alikunju, Saleena, Morsey, Brenda M., Brodie, Michael R., Persidsky, Yuri, Haorah, James
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022486/
https://ncbi.nlm.nih.gov/pubmed/20379791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-010-9213-z
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