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SHIP deficiency causes Crohn's disease-like ileitis

BACKGROUND: Inflammatory bowel disease (IBD) can arise from genetic mutations that compromise intestinal epithelial cell integrity or immune regulation. SHIP has previously been shown to play a pivotal role in limiting the number of immunoregulatory cells and their function. AIM: To determine whethe...

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Detalhes bibliográficos
Main Authors: Kerr, William G, Park, Mi-Young, Maubert, Monique, Engelman, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022365/
https://ncbi.nlm.nih.gov/pubmed/20940287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2009.202283
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