Mechanisms of Myogenic Tone of Coronary Arteriole: Role of Down Stream Signaling of the EGFR Tyrosine Kinase

BACKGROUND AND PURPOSE: We previously showed that epidermal growth factor receptor tyrosine kinase (EGFRtk) is essential in the development of myogenic tone. GRB2-SOS, protein kinase B (Akt), Janus kinase (JAK), and Signal Transducer and Activator of Transcription 3 (STAT3) are activated by stretch....

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Bibliografiske detaljer
Main Authors: Amin, Ali H, Elmageed, Zakaria Y Abd, Partyka, Megan, Matrougui, Khalid
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022328/
https://ncbi.nlm.nih.gov/pubmed/21067705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2010.11.001
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