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Mechanisms of Myogenic Tone of Coronary Arteriole: Role of Down Stream Signaling of the EGFR Tyrosine Kinase
BACKGROUND AND PURPOSE: We previously showed that epidermal growth factor receptor tyrosine kinase (EGFRtk) is essential in the development of myogenic tone. GRB2-SOS, protein kinase B (Akt), Janus kinase (JAK), and Signal Transducer and Activator of Transcription 3 (STAT3) are activated by stretch....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3022328/ https://ncbi.nlm.nih.gov/pubmed/21067705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2010.11.001 |
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