WY-14643, a Potent Peroxisome Proliferator Activator Receptor-α PPAR-α Agonist Ameliorates the Inflammatory Process Associated to Experimental Periodontitis

We have investigated the effects of WY14643, a potent peroxisome proliferator activator receptor-α (PPAR-α) agonist, in a rat model of ligature-induced periodontitis. Male Sprague-Dawley rats were lightly anaesthetized with pentobarbitone (35 mg/kg). Sterile, 2-0 black braided silk thread was placed...

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Autores principales: Briguglio, Enrico, Di Paola, Rosanna, Paterniti, Irene, Mazzon, Emanuela, Oteri, Giacomo, Cordasco, Giancarlo, Cuzzocrea, Salvatore
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022213/
https://ncbi.nlm.nih.gov/pubmed/21253492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/193019
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