Hydrodynamic Delivery of Chitosan-Folate-DNA Nanoparticles in Rats with Adjuvant-Induced Arthritis

50 kDa chitosan was conjugated with folate, a specific tissue-targeting ligand. Nanoparticles such as chitosan-DNA and folate-chitosan-DNA were prepared by coacervation process. The hydrodynamic intravenous injection of nanoparticles was performed in the right posterior paw in normal and arthritic r...

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Autores principales: Shi, Qin, Wang, Huijie, Tran, Covi, Qiu, Xingping, Winnik, Françoise M., Zhang, Xiaoling, Dai, Kerong, Benderdour, Mohamed, Fernandes, Julio C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022186/
https://ncbi.nlm.nih.gov/pubmed/21274258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/148763
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