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Choline Modulation of the Aβ P1-40 Channel Reconstituted into a Model Lipid Membrane

Nicotinic acetylcholine receptors (AChRs), implicated in memory and learning, in subjects affected by Alzheimer's disease result altered. Stimulation of α7-nAChRs inhibits amyloid plaques and increases ACh release. β-amyloid peptide (AβP) forms ion channels in the cell and model phospholipid me...

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Autors principals: Meleleo, Daniela, Notarachille, Gabriella, Micelli, Silvia
Format: Artigo
Idioma:Inglês
Publicat: SAGE-Hindawi Access to Research 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022179/
https://ncbi.nlm.nih.gov/pubmed/21253469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/752804
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