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The Metabolism of Proinsulin and Insulin by the Liver

The removal of bovine proinsulin by the isolated perfused rat liver has been studied and the results compared with the removal of insulin. At high concentrations of insulin (> 180 ng/ml) the removal process was saturated and the t½ varied between 35 and 56 min. With low initial insulin levels the...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Rubenstein, A. H., Pottenger, L. A., Mako, M., Getz, G. S., Steiner, D. F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1972
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5014618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106886
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